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AI creates 16 new viruses that never existed in nature after learning DNA’s pattern from 9 trillion nucleotides — experts warn such applications are way ahead of necessary guardrails

TL;DR

Researchers used the Evo AI models, trained on trillions of DNA building blocks, to design entirely new viral genomes. Sixteen of them became viable bacteriophages capable of infecting and reproducing inside E. coli, a solid demonstration that generative models can produce functioning organisms at genome scale. Experts warn that such applications are running well ahead of the guardrails meant to contain them.

Nauti's Take

The potential is substantial: if models can design functioning phages, targeted therapies against resistant bacteria move within reach. The risk sits on the other side of the same capability, because the barrier to constructing novel pathogens drops just as fast while biosecurity controls clearly lag behind.

Medicine and biotech gain a powerful tool here, and regulators and labs need to tighten access rules now.

Sources